师资队伍

鄢仁祥

姓名:鄢仁祥

性别:男

职称:副研究员、硕士生导师

学历:博士

电子邮件:yanrenxiang@fzu.edu.cn

研究方向:生物信息学、蛋白质结构及功能预测、计算基因组分析

教育工作经历:

2013.6 ~ 现今  福州大学,从事教学及科学研究工作。

2011.9 ~ 2013.4 美国密歇根大学,结构生物信息学, 访问研究/博士后。

2007.9 ~ 2012.6 中国农业大学,生物信息学, 博士。

2003.9 ~ 2007.6 福建农林大学,生科院国家理科基地班,学士。

教学简介:

主讲:《生物信息学》,本科生课程(2013~2017)。

参讲:《基因组学》,研究生课程(2015~2017年春)。

参讲:《应用蛋白质化学》,研究生课程(2014,2016年春)。

参讲:《专家系列讲座》,本科生课程(2016年秋)。

科研简介:

目前研究方向包括蛋白质结构与功能预测、计算基因组学等。精通Neural Network, Support Vector Machine和Random   Forest等统计预测算法。

社会兼职:

担任Scientific Reports、BMC Bioinformatics、Molecular Biosystems、PLOS ONE、IEEE/ACM   Transactions on Computational Biology and Bioinformatics、China Journal of Bioinformatics、Advances and Applications in Bioinformatics   and Chemistry、BioMed Research International、Current Bioinformatics、中国生物化学与分子生物学报、浙江农业学报 等期刊审稿人。

主持科研项目:

1、国家自然科学基金、31500673、G蛋白偶联受体结构及与药物配体结合的计算研究。

2、福州大学科技发展基金项目、2014-XY-15、膜蛋白结构与功能预测新算法的开发。

3、福建省教育厅科技项目、JA14049、膜蛋白序列、结构与功能关系的挖掘。

4、福州大学人才基金项目、XRC-1336、与疾病相关的生物信息学平台的构建。

代表性论文(*通讯作者)

1.Renxiang Yan*, Xiaofeng Wang, Lanqing   Huang, Yarong Tian and Weiwen Cai (2017) Transmembrane region prediction by   using sequence-derived features and machine learning methods,RSC Advances, DOI:10.1039/C7RA03883F, 29200-29211

2.Guozeng Wang, Jingjing Wu, Renxiang Yan, Juan Lin and Xiuyun Ye   (2016) A novel multi-domain high molecular, salt-stable alkaline xylanase   from Alkalibacterium sp. SL3. Front. Microbiol doi:   10.3389/fmicb.2016.02120

1.3.Renxiang Yan*, Xiaofeng Wang,

Weiming   Xu, Weiwen Cai, Juan Lin, Jian Li, Jiangning Song* (2016), A neural network learning approach for   improving the prediction of residue depth based on sequence-derived features,   RSC Advances, 67729-67738

2.4.Xiaofeng Wang, Renxiang Yan, Jian Li, Jiangning   Song (2016) SOHPRED: a new bioinformatics tool for the characterization and   prediction of human S-sulfenylation sites, Mol Biosyst, 12(9):2849-58.   doi: 10.1039/c6mb00314a

3.5. Xiaofeng Wang, Renxiang Yan, Jiangning   Song (2016) DephosSite: a machine learning approach for discovering phosphotase-specific   dephosphorylation sites, Scientific   Reports, 23510,doi:10.1038/srep23510.

6.许伟明,王晓锋,林娟,蔡伟文,鄢仁祥*(2016)   G蛋白偶联受体计算研究的进展和前瞻. 中国生物信息学,14(1):31-38.

7. Guozeng Wang, Qiaohuang Wang,   Xianju Lin, Tzi Bun Ng, Renxiang Yan,   Juan Lin, Xiuyun Ye (2016) A novel cold-adapted and highly salt-tolerant   esterase from Alkalibacterium sp. SL3 from the sediment of a soda lake. Scientific Reports,6,   19494.

8. Renxiang Yan*, Xiaofeng Wang, Weiming Xu, Juan Lin,   and Weiwen Cai (2015) A short review of protein fold recognition   methods. Chinese Journal of Bioinformatics. 13(4) DOI:10.3 969, 231-238.

9.Renxiang Yan*, Xiaofeng Wang,   Lanqing Huang, Feidi Yan, Xiaoyu Xue, and Weiwen Cai (2015) Prediction of   structural features and application to outer membrane protein identification.   Scientific Reports, 5, 11586. IF: 5.078

10.Renxiang   Yan, Jiangning Song, Weiwen Cai and Ziding Zhang (2015) A short review on   protein secondary structure prediction methods. Pattern   Recognition in Computational Molecular Biology: Techniques and Approaches (Wiley   Series in Bioinformatics). Chapter 6. DOI: 11.1002/9781119078845.ch6, ISBN:   978-1-118-89368-5,99-112.

11. Xiaofeng Wang*, Yuan Zhou, Renxiang Yan* (2015) AAFreqCoil:   a new classifier to distinguish parallel dimeric and trimeric coiled coils. Mol Biosyst, 11(7):1794-801.

12.Jianyi   Yang, Renxiang Yan, Ambrish Roy,   Dong Xu, Jonathan Poisson and Yang Zhang (2015) The I-TASSER Suite: protein   structure and function prediction. Nature Methods, 12, 7–8. IF:25.9.

13. Renxiang Yan*, Xiaofeng Wang, Lanqing   Huang, Jun Lin, Weiwen Cai and Ziding Zhang (2014) GPCRserver: an accurate   and novel G protein-coupled receptor predictor. Mol   Biosyst10: 2495-2504. IF:3.18.

14. Renxiang Yan*, Jun Lin, Zhen Chen,   Xiaofeng Wang, Lanqing Huang, Weiwen Cai and Ziding Zhang (2014) Prediction   of outer membrane proteins by combining the position- and composition-based   features of sequence profiles. Mol Biosyst, 10: 1004-1013. IF:3.18.

15.   Renxiang Yan*, Lanqing Huang,   Xiaofeng Wang and Weiwen Cai (2014) EasyAlign: an easy and novel fold   recognition tool. The 8th International Conference on Bioinformatics and   Biomedical Engineering (iCBBE 2014 Proceedings Paper) ISBN:978-1-60595-194-2   Page57-62.

16. Renxiang Yan, Dong Xu, Jianyi Yang,   Sara Walker and Yang Zhang (2013)   A comparative assessment and analysis   of 20 representative sequence alignment methods for protein structure   prediction. Scientific Reports,   3: 2619. IF: 5.078.

17. Renxiang Yan, Zhen Chen, Ziding Zhang   (2011) Outer membrane proteins can be simply identified using secondary   structure element alignment. BMC Bioinformatics, 12:76. IF:2.751.

18.   Renxiang Yan, Jing Liu,Yi-Min Tao (2011)   Improving PSI-BLAST's Fold Recognition Performance through Combining   Consensus Sequences and Support Vector Machine , Interdisciplinary Research   and Applications in Bioinformatics, Computational Biology, and Environmental   Sciences, 51-59.

19. Renxiang Yan, Jing-Na Si, Chuan Wang   and Ziding Zhang (2009) DescFold: A web server for protein fold recognition. BMC   Bioinformatics,10:416. IF:3.02.

20. Jing-Na   Si, Renxiang Yan, Chuan Wang, Ziding   Zhang, and Xiao-Dong Su (2009) TIM-Finder: A novel method to recognize   TIM-barrel proteins. BMC Structural Biology, 9:73.   IF:2.22.

21. Wang   Chuan, Renxiang Yan, XiaoFeng   Wang, JingNa Si and Zhang Z. (2011) Comparison of linear gap penalties and   profile-based variable gap penalties in profile-profile alignments. Comput   Biol Chem, 35: 308-318. IF: 1.59.

22. Zhen Chen,   YongZhi Chen, XiaoFeng Wang, Chuan Wang, Renxiang   Yan and Ziding Zhang (2011) Prediction of ubiquitination sites by using   the composition of k-spaced amino   acid pairs. PLOS ONE,6: e22930. IF:3.53.

23. Yang   Zhang, Dong Xu, Jianyi Yang, Ambrish Roy and Renxiang Yan Protein structure predictions by a combination of   I-TASSER and QUARK pipelines. CASP 10 abstract,   2012, [www.predictioncenter.org/casp10/doc/CASP10_Abstracts.pdf].

24. Xiaofeng Wang, Zhen Chen, Chuan Wang,Renxiang Yan, ZidingZhang and   Jiangning Song (2011) Predicting residue-residue contacts and helix-helix   interactions in transmembrane proteins using an integrative feature-based   random forest approach. PLOS ONE, 6: e26767.   IF:3.53.

25. 谢勇,洪晓昆,鄢仁祥,林娟 重组琼胶酶rAgaN3基因的生物信息学分析 中国生物信息学,   2017,15(1):16-26

26.鄢仁祥*,王晓锋,陈震,蔡伟文,林娟(2017),《蛋白质结构生物信息学》,福建科学技术出版社, ISBN:978-7-5335-5096-7(http://genomics.fzu.edu.cn/bioinformatics.pdf.

获奖情况:

1.2016年申请获得软件著作权一项(登记号2016SR219894)。

2.2016年获得《中国生物信息学》杂志优秀审稿专家称号。

3.2010年获得“中国农业大学博士生国际交流项目”资助,赴美波斯顿参加ISMB会议。

4.获得IBM SPSS Modeler和Oracle   Professional Java Programmer等8种计算机水平认证。

5.2009~2010作为主要完成人之一,申请了两项生物信息学软件著作权, 登记号分别为2009SRBJ8227以及2010SRBJ5799。

6.2009年获“中国农业大学博士生科研成就奖”奖学金。


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