师资队伍

鄢仁祥

 

姓名:鄢仁祥

性别:男

职称:副研究员、硕士生导师

学历:博士

电子邮件:yanrenxiang@fzu.edu.cn

研究方向:生物信息学、蛋白质结构及功能预测、计算基因组分析

教育工作经历:

2013.6 ~ 现今  福州大学,从事教学及科学研究工作。

2011.9 ~ 2013.4 美国密歇根大学,结构生物信息学, 访问研究/博士后。

2007.9 ~ 2012.6 中国农业大学,生物信息学, 博士。

2003.9 ~ 2007.6 福建农林大学,生科院国家理科基地班,学士。

教学简介:

主讲:《生物信息学》,本科生课程(2013~2017)。

参讲:《基因组学》,研究生课程(2015~2017年春)。

参讲:《应用蛋白质化学》,研究生课程(2014,2016年春)。

参讲:《专家系列讲座》,本科生课程(2016年秋)。

科研简介:

目前研究方向为基因组学和蛋白质组学的计算研究。精通Neural Network, Support Vector Machine和Random Forest等统计预测算法。

社会兼职:

担任Scientific Reports、BMC Bioinformatics、Molecular Biosystems、PLOS ONE、IEEE/ACM Transactions on Computational Biology and Bioinformatics、China Journal of Bioinformatics、Advances and Applications in Bioinformatics and Chemistry、BioMed Research International、Current Bioinformatics、Journal of Information Security中国生物化学与分子生物学报、浙江农业学报 等期刊审稿人。

主持科研项目:

1、国家自然科学基金、31500673、G蛋白偶联受体结构及与药物配体结合的计算研究。

2、福州大学科技发展基金项目、2014-XY-15、膜蛋白结构与功能预测新算法的开发。

3、福建省教育厅科技项目、JA14049、膜蛋白序列、结构与功能关系的挖掘。

4、福州大学人才基金项目、XRC-1336、与疾病相关的生物信息学平台的构建。

代表性论文(*通讯作者)

1.Xiaofeng Wang*, Renxiang Yan*(2018)RFAthM6A: a new tool for predicting m6A sites in Arabidopsis thaliana. Plant Molecular Biology, 1–11 doi.org/10.1007.

2.Renxiang Yan*, Xiaofeng Wang, Lanqing Huang, Yarong Tian and Weiwen Cai (2017) Transmembrane region prediction by using sequence-derived features and machine learning methodsRSC Advances, 7(46)29200-29211

3.Guozeng Wang, Jingjing Wu, Renxiang Yan, Juan Lin and Xiuyun Ye (2016) A novel multi-domain high molecular, salt-stable alkaline xylanase from Alkalibacterium sp. SL3. Front. Microbiol doi: 10.3389/fmicb.2016.02120

1.4.Renxiang Yan*, Xiaofeng Wang,

Weiming Xu, Weiwen Cai, Juan Lin et al (2016), A neural network learning approach for improving the prediction of residue depth based on sequence-derived features, RSC Advances, 67729-67738

2.5.Xiaofeng Wang, Renxiang Yan, Jian Li, Jiangning Song (2016) SOHPRED: a new bioinformatics tool for the characterization and prediction of human S-sulfenylation sites, Mol Biosyst, 12(9):2849-58. doi: 10.1039/c6mb00314a

3.6. Xiaofeng Wang, Renxiang Yan, Jiangning Song (2016) DephosSite: a machine learning approach for discovering phosphotase-specific dephosphorylation sites, Scientific Reports, 23510,doi:10.1038/srep23510.

7.许伟明,王晓锋,林娟,蔡伟文,鄢仁祥*(2016) G蛋白偶联受体计算研究的进展和前瞻. 中国生物信息学,14(1):31-38.

8. Guozeng Wang, Qiaohuang Wang, Xianju Lin, Tzi Bun Ng, Renxiang Yan, Juan Lin, Xiuyun Ye (2016) A novel cold-adapted and highly salt-tolerant esterase from Alkalibacterium sp. SL3 from the sediment of a soda lake. Scientific Reports,6, 19494.

9. Renxiang Yan*, Xiaofeng Wang, Weiming Xu, Juan Lin, and Weiwen Cai (2015) A short review of protein fold recognition methods. Chinese Journal of Bioinformatics. 13(4) DOI:10.3 969, 231-238.

10.Renxiang Yan*, Xiaofeng Wang, Lanqing Huang, Feidi Yan, Xiaoyu Xue, and Weiwen Cai (2015) Prediction of structural features and application to outer membrane protein identification. Scientific Reports, 5, 11586. IF: 5.078

11.Renxiang Yan, Jiangning Song, Weiwen Cai and Ziding Zhang (2015) A short review on protein secondary structure prediction methods. Pattern Recognition in Computational Molecular Biology: Techniques and Approaches (Wiley Series in Bioinformatics). Chapter 6. doi: 1.1002/9781119078845.ch6, ISBN: 978-1-118-89368-5,99-112.

12. Xiaofeng Wang*, Yuan Zhou, Renxiang Yan* (2015) AAFreqCoil: a new classifier to distinguish parallel dimeric and trimeric coiled coils. Mol Biosyst, 11(7):1794-801.

13.Jianyi Yang, Renxiang Yan, Ambrish Roy, Dong Xu, Jonathan Poisson and Yang Zhang (2015) The I-TASSER Suite: protein structure and function prediction. Nature Methods, 12, 7–8. IF:25.9.

14. Renxiang Yan*, Xiaofeng Wang, Lanqing Huang, Jun Lin, Weiwen Cai and Ziding Zhang (2014) GPCRserver: an accurate and novel G protein-coupled receptor predictor. Mol Biosyst10: 2495-2504. IF:3.18.

15. Renxiang Yan*, Jun Lin, Zhen Chen, Xiaofeng Wang, Lanqing Huang, Weiwen Cai and Ziding Zhang (2014) Prediction of outer membrane proteins by combining the position- and composition-based features of sequence profiles. Mol Biosyst, 10: 1004-1013. IF:3.18.

16. Renxiang Yan*, Lanqing Huang, Xiaofeng Wang and Weiwen Cai (2014) EasyAlign: an easy and novel fold recognition tool. The 8th International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2014 Proceedings Paper) ISBN:978-1-60595-194-2, 57-62.

17. Renxiang Yan, Dong Xu, Jianyi Yang, Sara Walker and Yang Zhang (2013) A comparative assessment and analysis of 20 representative sequence alignment methods for protein structure prediction. Scientific Reports, 3: 2619. IF: 5.078.

18. Renxiang Yan, Zhen Chen, Ziding Zhang (2011) Outer membrane proteins can be simply identified using secondary structure element alignment. BMC Bioinformatics, 12:76. IF:2.751.

19. Renxiang Yan, Jing Liu,Yi-Min Tao (2011) Improving PSI-BLAST's Fold Recognition Performance through Combining Consensus Sequences and Support Vector Machine , Interdisciplinary Research and Applications in Bioinformatics, Computational Biology, and Environmental Sciences, 51-59.

20. Renxiang Yan, Jing-Na Si, Chuan Wang and Ziding Zhang (2009) DescFold: A web server for protein fold recognition. BMC Bioinformatics,10:416. IF:3.02.

21. Jing-Na Si, Renxiang Yan, Chuan Wang, Ziding Zhang, and Xiao-Dong Su (2009) TIM-Finder: A novel method to recognize TIM-barrel proteins. BMC Structural Biology, 9:73. IF:2.22.

22. Wang Chuan, Renxiang Yan, XiaoFeng Wang, JingNa Si and Zhang Z. (2011) Comparison of linear gap penalties and profile-based variable gap penalties in profile-profile alignments. Comput Biol Chem, 35: 308-318. IF: 1.59.

23. Zhen Chen, YongZhi Chen, XiaoFeng Wang, Chuan Wang, Renxiang Yan and Ziding Zhang (2011) Prediction of ubiquitination sites by using the composition of k-spaced amino acid pairs. PLOS ONE,6: e22930. IF:3.53.

24. Yang Zhang, Dong Xu, Jianyi Yang, Ambrish Roy and Renxiang Yan Protein structure predictions by a combination of I-TASSER and QUARK pipelines. CASP 10 abstract, 2012, [www.predictioncenter.org/casp10/doc/CASP10_Abstracts.pdf].

25. Xiaofeng Wang, Zhen Chen, Chuan Wang,Renxiang Yan, ZidingZhang and Jiangning Song (2011) Predicting residue-residue contacts and helix-helix interactions in transmembrane proteins using an integrative feature-based random forest approach. PLOS ONE, 6: e26767. IF:3.53.

26. 谢勇,洪晓昆,鄢仁祥,林娟 重组琼胶酶rAgaN3基因的生物信息学分析 中国生物信息学, 2017,15(1):16-26

27.鄢仁祥*,王晓锋,陈震,蔡伟文,林娟(2017),《蛋白质结构生物信息学》,福建科学技术出版社, ISBN:978-7-5335-5096-7/attach/2018/01/17/299231.pdf.

获奖情况:

1.2016年申请获得软件著作权一项(登记号2016SR219894)。

2.2016年获得《中国生物信息学》杂志优秀审稿专家称号。

3.2010年获得“中国农业大学博士生国际交流项目”资助,赴美波斯顿参加ISMB会议。

4.获得IBM SPSS Modeler和Oracle Professional Java Programmer等8种计算机水平认证。

5.2009~2010作为主要完成人之一,申请了两项生物信息学软件著作权, 登记号分别为2009SRBJ8227以及2010SRBJ5799。

6.2009年获“中国农业大学博士生科研成就奖”奖学金。

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