教育工作经历：

2018/09-至今，福州大学，生物科学与工程学院，研究员

2014/07-2018/09，中国农业科学院生物技术研究所，研究员

2012/09-2014/06，韩国国立庆尚大学，博士后

2007/09-2012/09，韩国国立庆尚大学，植物分子生物学，博士

2004/09-2007/09，中国科学院武汉病毒研究所，分子生物学与生物化学，硕士

1999/09-2003/09，西安交通大学，生物工程，学士

科研简介：

长期从事传染病防治医学研究，研究团队构建了病原体分子诊断与生物传感器、生物医用材料、器官芯片等前沿技术平台，在艾滋病、慢性乙型肝炎、登革热等重大传染病防控研究中取得多项突破。近年来，团队聚焦超快核酸检测、病原体—宿主免疫互作、多功能水凝胶、微流控器官芯片等方向，并将相关技术拓展应用于老年康复医学，形成了鲜明的科研特色与优势。已在Developmental Cell、Advanced Science、Nature Communications、Chinese Medical Journal、Ageing Research Reviews、Trends in Biotechnology、Trends in Microbiology、Analytica Chimica Acta等国际权威期刊发表SCI论文50余篇，获国家发明专利授权2项；参与完成的科研成果两度荣获福建省医学科技奖三等奖。

人才称号：

人社部高层次留学归国人员，中国农业科学院“青年英才计划”，全国青年岗位能手，福建省高层次人才，福建省“闽江学者特聘教授”。

社会兼职：

担任Frontiers系列期刊编委及多种国际学术期刊审稿人。

科研项目：

先后主持或参与国家重点研发计划、福建省卫生教育联合攻关项目等多项国家及省部级科研课题。

代表性论文：

1.Cong Chen, Cai Jiang, Qing Xiang, Yue Hu, Huijuan Wu, Chunxiu Huang, Huanghao Zhou, Ying Xu, Meijin Hou, Weilin Liu, Xiao Han*. METTL16-m6A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant mice. BMC Biology, 2026, 24(1): 41.

2.Qinyan Chen, Qiong Lin, Yibin Zeng, Haining Li, Xiao Han*, Dianping Tang, Gaoda Ju. Pencil-drawn paper-based portable photoelectrochemical immunoassay of carbohydrate antigen 19-9 based on TiO2 hollow cube homogeneous junctions. Analytica Chimica Acta, 2026, 1398: 345288.

3.Feichi Hu, Xianjin Wang, Sangsang Zheng, Xiao Han, Zhichao Yu, Dianping Tang, Xiwen Jiang. D-π conjugated S-type ZnO-polydopamine heterojunctions with enzymatic cascade amplification for enhanced photoelectrochemical immunoassay. Biosensors and Bioelectronics, 2026, 307: 118745.

4.Miao Zhang, Wenqian Liu, Cuicui Wang, Shujin Lin, Ying Chen, Heran Cui, Chenggang Xiang, Yujia Ma, Xiaojun Li, Yongzhen Lu, Xiao Han, Yihan Dong, Lihong Gao, Wenna Zhang. Root-to-shoot mobile mRNA CmoKARI1 promotes JA-Ile biosynthesis to confer chilling tolerance in grafted cucumbers. Nature Communications, 2025, 16(1): 7782.

5.Shujin Lin, Qian Zhang, Shiyan Bai, Liwen Yang, Guannan Qin, Liyuan Wang, Wenbin Wang, Cui Cheng, Da Zhang, Chunhua Lu, Jifeng Yuan, Jingying Li, Huanghao Yang, Xiaofeng Gu, Xiao Han*. Beyond species and spatial boundaries: Enabling long-distance gene silencing in plants via guanidinium-siRNA nanoparticles. Plant Biotechnology Journal, 2025, 23(4): 1165-1177.

6.Huanghao Zhou, Xiao Han, Chunxiu Huang, Huijuan Wu, Yue Hu, Cong Chen, Jing Tao. Exercise-induced adaptive response of different immune organs during ageing. Ageing Research Reviews, 2024, 102: 102573.

7.Shujin Lin, Dan Feng, Xiao Han*, Ling Li, Yao Lin, Haibing Gao. Microfluidic platform for omics analysis on single cells with diverse morphology and size: A review. Analytica Chimica Acta, 2024, 1294: 342217.

8.Yahong Chen, Xin Li, Shuran Liu, Wen Ao, Jing Lin, Zhenting Li, Shouli Wu, Hanhui Ye, Xiao Han, Dongliang Li. An atlas of immune cell transcriptomes in human immunodeficiency virus-infected immunological non-responders identified marker genes that control viral replication.Chinese Medical Journal, 2023, 136(22): 2694-2705.

9.Baolei Jia, Yuanqiang Zou, Xiao Han, Jin-Woo Bae, Che Ok Jeon. Gut microbiome-mediated mechanisms for reducing cholesterol levels: implications for ameliorating cardiovascular disease. Trends in Microbiology, 2023, 31(1): 76-91.

10.Baolei Jia, Xiao Han, Kyung Hyun Kim, Che Ok Jeon. Discovery and mining of enzymes from the human gut microbiome. Trends in Biotechnology, 2022, 40(2): 240-254.

11.Zhe Liang, Yuke Geng, Changmian Ji, Hai Du, Chui Eng Wong, Qian Zhang, Ye Zhang, Pingxian Zhang, Adeel Riaz, Sadaruddin Chachar, Yike Ding, Jing Wen, Yunwen Wu, Mingcheng Wang, Hongkun Zheng, Yanmin Wu, Viktor Demko, Lisha Shen, Xiao Han, Pengpeng Zhang, Xiaofeng Gu, Hao Yu. Mesostigma viride Genome and Transcriptome Provide Insights into the Origin and Evolution of Streptophyta. Advanced Science, 2020, 7(1): 1901850.

12.Xiao Han, Jae-Yean Kim. Integrating Hormone- and Micromolecule-Mediated Signaling with Plasmodesmal Communication. Molecular Plant, 2016, 9(1): 46-56.

13.Xiao Han, Tae Kyung Hyun, Minhua Zhang, Ritesh Kumar, Eun-ji Koh, Byung-Ho Kang, William J Lucas, Jae-Yean Kim. Auxin-callose-mediated plasmodesmal gating is essential for tropic auxin gradient formation and signaling. Developmental Cell, 2014, 28(2): 132-146.

14.Xiao Han, Dhinesh Kumar, Huan Chen, Shuwei Wu, Jae-Yean Kim. Transcription factor-mediated cell-to-cell signalling in plants. Journal of Experimental Botany, 2014, 65(7): 1737-1749.