教育工作经历：

2026.01~至今，福州大学，生物科学与工程学院，讲师

2023.07~2025.11，浙江大学，生物系统工程与食品科学学院，农业工程，博士后/助理研究员

2018.09~2023.06，浙江大学，生物系统工程与食品科学学院，食品科学，博士（硕博连读）

2014.09~2018.06，海南大学，食品学院，食品质量与安全，学士

教学简介：无

本科生课程：福州大学至诚学院《营养学》、《食品化学》

研究生课程：福州大学《食品分子生物学》

科研简介：

主要研究方向为（1）食品浆果来源花色苷类多酚（如矢车菊素-3-O-葡萄糖苷）的抗氧化、抗炎与糖脂代谢调控活性及其分子机制；（2）浆果花色苷对食品污染物微塑料诱导的肠道菌群失调、代谢紊乱、结肠炎等毒性的干预作用及机制；（3）牛乳、蜂王浆、栀子等来源外泌体的提取、生物活性及其靶向递送应用等。合计发表SCI论文34篇，其中以第一或通讯作者（含共同）在Journal of Agricultural and Food Chemistry、Journal of Hazardous Materials、Materials Today Bio、Food & Function等期刊发表论文12篇，总引用数780余次，个人H-指数18。主持中国博士后科学基金面上项目1项，参与国家自然科学基金面上项目1项；申请国家发明专利3项（1项已授权）。

社会兼职：

（1）担任Frontier in Cellular and Infection Microbiology（IF=4.9，中科院2区）期刊，专刊客座主编；

（2）担任Journal of Hazardous Materials、Food Research International、LWT-Food Science and Technology、Food Bioscience、The Journal of Nutritional Biochemistry等期刊审稿人。

主持科研项目：

（1）福州大学引进人才启动项目（2026-2028，主持）

（2）中国博士后科学基金第76批面上项目（2024.11-2025.11，主持）

（3）杭州市博士后科研启动项目（2023.7-2025.11，主持）

代表性论文：

[1] Wu Yuanjie#, Chen Wen #,*, Ye Xiang, Hao Xingkai, Wen Yuhao, Wu Jian, Li Danyang, and Xu Lizhou*. Targeted C3G delivery by engineered milk exosomes for effective therapy in microplastics-induced colitis. Materials Today Bio, 2026, 36, 102639.

[2] Chen Wen, Wang Haobo, Ye Xiang, Hao Xingkai, Yan Fujie, Wu Jian, Li Danyang, Wang Yan* & Xu Lizhou*. Gardenia-derived extracellular vesicles exert therapeutic effects on dopaminergic neuron apoptosis-mediated Parkinson's disease. npj Parkinson's Disease, 2025, 11(1), 200.

[3] Chen Wen, Zheng Xiaodong, Yan Fujie, Xu Lizhou* & Ye Xiang*. Modulation of Gut Microbial Metabolism by Cyanidin-3-O-Glucoside in Mitigating Polystyrene-Induced Colonic Inflammation: Insights from 16S rRNA sequencing and Metabolomics. Journal of Agricultural and Food Chemistry, 2024, 72(13),7140–7154.

[4] Ye Xiang#, Chen Wen#, Huang Xufan, Yan Fujie, Deng Shuiguang & Zheng Xiaodong*, Shan Pengfei*. Anti-diabetic effect of anthocyanin cyanidin-3-O-glucoside: data from insulin resistant hepatocyte and diabetic mouse. Nutrition & Diabetes, 2024, 14(1), 7.

[5] Chen Wen, Zhu Ruiyu, Ye Xiang, Sun Yunhao, Tang Qiong, Liu Yangyang, Yan Fujie, Yu Ting, Zheng Xiaodong, Tu Pengcheng*. Food-derived cyanidin-3-O-glucoside reverses microplastic toxicity via promoting discharge and modulating the gut microbiota in mice. Food & Function, 2022, 13, 1447.

[6] Ye Xiang#, Wen Chen#, Tu Pengcheng, Jia Ruoyi, Liu Yangyang, Tang Qiong, Chen Chuan, Yang Caihong, Zheng Xiaodong*. Antihyperglycemic effect of an anthocyanin, cyanidin-3-O-glucoside, is achieved by regulating GLUT-1 via Wnt/β-catenin-WISP1 signaling pathway. Food & Function, 2022, 13, 4612–4623.

[7] Chen Wen, Ye Xiang, Tang Qiong, Yu Ting, Pengcheng Tu* & Zheng Xiaodong*. Cyanidin-3-O-glucoside reduces nanopolystyrene-induced toxicity and accumulation: roles of mitochondrial energy metabolism and cellular efflux. Environmental Science: Nano, 2022, 9, 2572.

[8] Chen Wen#, Chen Zhen#, Shan Shuo, Wu Aibo, Zhao Chao, Ye Xiang, Zheng Xiaodong & Zhu Ruiyu*. Cyanidin-3-O-glucoside promotes stress tolerance and lifespan extension of Caenorhabditis elegans exposed to polystyrene via DAF-16 pathway. Mechanisms of Ageing and Development, 2022, 207, 111723.

[9] Chen Wen, Tu Pengcheng, Ye Xiang, Tang Qiong, Yu Ting & Zheng Xiaodong*. Cyanidin-3-O-glucoside impacts fecal discharge of polystyrene microplastics in mice: Potential role of microbiota-derived metabolites. Toxicology and Applied Pharmacology, 2022, 453, 116212.

[10] Chen Wen#, Chu Qiang#, Ye Xiang, Sun Yuhao, Liu Yangyang, Jia Ruoyi, Li Yonglu, Tu Pengcheng, Tang Qiong, Yu Ting, Chen Chuan, Zheng Xiaodong*. Canidin-3-glucoside prevents nano-plastics induced toxicity via activating autophagy and promoting discharge. Environmental Pollution, 2021, 274, 116524.

[11] Chu Qiang# , Chen Wen# , Jia Ruoyi, Ye Xiang, Li Yonglu, Liu Yangyang, Jiang Yong, Zheng Xiaodong*. Tetrastigma hemsleyanum leaves extract against acrylamide-induced toxicity in HepG2 cells and Caenorhabditis elegans. Journal of Hazardous Materials, 2020, 393, 122364.

[12] 陈文, 朱莉娅, 韩宇, 刘东莉*. 表面增强拉曼光谱技术应用于西瓜中杀螟硫磷农药残留的检测. 食品科技, 2018,43(01):320-325.

授权专利情况：

[1] 栀子源细胞外囊泡在制备防治神经退行性疾病药物中的应用. 2025, 专利号：ZL 2024 11248476.7

[2] miRNA、包括其的miRNA组合产品及应用. 2025, 申请号: 202510570024.9

[3] 一种乳房炎miRNA标志物的传感检测用试剂盒、传感检测方法. 2025, 申请号: 202511877122.3

获奖情况：

[1] 2025中国商业联合会科技进步二等奖（参与）

[2] 浙江大学优秀毕业研究生

[3] 浙江大学启真奖学金、康而达奖学金

[4] 国家留学基金委公派出国留学资格（CSC）

[5] 海南大学优秀毕业生

[6] 国家奖学金