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师资队伍

生物技术与工程系

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  • 王国增

    性别:男

    学历:博士

    电子邮件:wanggz@fzu.edu.cn

    研究方向:1.极端酶功能及应用;2.合成生物学;3.酶工程

  • 详细资料

    教育工作经历:

    2002-2006:东北农业大学,学士

    2006-2011:中国农业科学院研究生院,博士

    2011-2013:中国农业科学院生物技术研究所,助理研究员

    2017-2018:德国汉堡大学,访问学者

    2013-今:福州大学生物科学与工程学院,副研究员

    教学简介:

    本科生课程:蛋白质与酶工程,基因工程

    研究生课程:现代微生物生物技术,应用蛋白质化学

    科研简介:

    在极端环境微生物酶发掘、酶的结构功能、合成生物学等领域进行了深入研究。主持国家自然基金青年基金项目1项,福建省高校杰出青年人才项目1项,福建省自然科学基金项目、校人才基金和校科技发展基金等共4项,作为课题骨干参加国家863项目1项。在Bioresource Technology、Scientific Reports、PLoS ONE、Applied Microbiology and Biotechnology、Biochemical and Biophysical Research Communications等刊物上发表SCI论文25篇,其中以第一作者或通讯作者发表17篇。申请发明专利6项, 其中获得授权4项。

    社会兼职:

    福建省微生物学会理事

    科研项目:

    1. 福建省自然科学基金,2019J01237,瘤胃微生物木聚糖酶基因在食物消化周期中的表达规律及功能特性研究,2019.06-2022.05,主持。

    2. 福建省高校杰出青年科研人才计划,SW2015-01,宏基因组技术发掘和利用盐碱湖中极端微生物碱性酶基因资源,2015.07-2017.12,主持。

    3. 福建省自然科学基金,2015J05066,大布苏盐碱湖底泥微生物宏基因组中新木聚糖酶基因克隆表达及其特性研究,2015.04-2018.03,主持。

    4. 国家自然科学基金青年基金项目,31301406,山羊瘤胃微生物宏基因组来源的低温木聚糖酶XynGR40冷适应机制的研究,2014.01-2016.12,主持。

    5、校人才基金,XRC-1326,盐碱湖微生物木聚糖酶基因多样性及新基因克隆和酶特性研究,2013.06-2015.08,主持。

    6、校科技发展基金,2013-XY-16,北极海洋底泥微生物新木聚糖酶基因克隆及酶学特性研究, 校科技发展基金, 2013.07-2015.12,主持

    7、国家高技术研究发展计划,2012AA022105,基因组多位点快速进化与改良,2012.12-2015.12,参与。

    专利

    (1)一种碱性耐盐普鲁兰酶PulA及其基因和应用,2017, 专利号: ZL201710584710.7

    (2)一种木聚糖酶XynMF10及其基因和应用,2017, 专利号: ZL 201710584732.3

    (3) 一种耐盐耐有机溶剂的低温碱性酯酶EstSL3及其基因和应用,2015, 专利号:ZL201510668911.6

    (4) 一种低温木聚糖酶XYNGR40及其基因和应用,2010,专利号:ZL201010238563.6

    (5) 一种高温碱性耐盐木聚糖酶XynSL4及其基因和应用,2014, 申请号: CN201410629920.X

    (6)一种极端嗜盐、耐表面活性剂的非钙离子依赖型α-淀粉酶及其基因和应用,2019, 申请号: CN109628429A

    以第一作者或通讯作者发表的论文:(*为通讯作者)

    [1] Ren Y, Luo H, Huang H, Hakulinen N, Wang Y, Wang Y, Su X, Bai Y, Zhang J, Yao B, Wang G*, Tu T*, Improving the catalytic performance of Proteinase K from Parengyodontium album for use in feather degradation, International Journal of Biological Macromolecules 154 (2020) 1586-1595

    [2] Xiao Q, Han J, Jiang C, Luo M, Zhang Q, He Z, Hu J*, Wang G*, Novel Fusion Protein Consisting of Metallothionein, Cellulose Binding Module, and Superfolder GFP for Lead Removal from the Water Decoction of Traditional Chinese Medicine. ACS Omega, 5 (2020) 2893-2898

    [3] G. Wang*, Y. Ren, T.B. Ng, W.R. Streit, X. Ye, High-throughput amplicon sequencing demonstrates extensive diversity of xylanase genes in the sediment of soda lake Dabusu, Biotechnology Letters 41(3) (2019) 409-418

    [4] G. Wang*, M. Luo, J. Lin, Y. Lin, R. Yan, W.R. Streit, X. Ye A new extremely halophilic, calcium-independent and surfactant- resistant alpha-amylase from Alkalibacterium sp. SL3, Journal of Microbiology and Biotechnology 29 (2019) 765-775.

    [5] J. Wu, R. C. Qiu, Y. Ren, Yan, X. Ye, G. Wang*, Novel salt-tolerant xylanase from a mangrove-isolated fungus Phoma sp. mf13 and its application in Chinese steamed bread, ACS Omega 3 (2018) 3708-3716.

    [6] G. Wang, J. Wu, R. Yan, J. Lin*, X. Ye*, A Novel Multi-domain High Molecular, Salt-Stable Alkaline Xylanase from Alkalibacterium sp. SL3, Frontiers in Microbiology 7 (2017) 2120.

    [7] G. Wang, J. Wu, J. Lin, X. Ye*, B. Yao*, The disruption of two salt bridges of the cold-active xylanase XynGR40 results in an increase in activity, but a decrease in thermostability, Biochemical and Biophysical Research Communications 481(1-2) (2016) 139-145.

    [8] G. Wang, Q. Wang, X. Lin, T.B. Ng, R. Yan, J. Lin*, X. Ye*, A novel cold-adapted and highly salt-tolerant esterase from Alkalibacterium sp. SL3 from the sediment of a soda lake, Scientific Reports 6 (2016) 19494.

    [9] X. Huang, J. Lin, X. Ye, G. Wang*, Molecular characterization of a thermophilic and salt- and alkaline-tolerant xylanase from Planococcus sp. sl4, a strain isolated from the sediment of a soda lake, Journal of Microbiology and Biotechnology 25(5) (2015) 662-671.

    [10] G. Wang, X. Huang, T.B. Ng, J. Lin*, X.Y. Ye*, High phylogenetic diversity of glycosyl hydrolase family 10 and 11 xylanases in the sediment of Lake Dabusu in China, PloS One 9(11) (2014) e112798.

    [11] G. Wang, K. Meng, H. Luo, Y. Wang, H. Huang, P. Shi, P. Yang, Z. Zhang*, B. Yao*, Phylogenetic diversity and environment-specific distributions of glycosyl hydrolase family 10 xylanases in geographically distant soils, PloS One 7(8) (2012) e43480.

    [12] Y. Li#, G. Wang#, J. Tian, H. Liu, H. Yang, Y. Yi, J. Wang, X. Shi, F. Jiang, B. Yao*, Z. Zhang*, Transcriptome analysis of the silkworm (Bombyx mori) by high-throughput RNA sequencing, PloS One 7(8) (2012) e43713.

    [13] G. Wang, K. Meng, H. Luo, Y. Wang, H. Huang, P. Shi, X. Pan, P. Yang, B. Yao*, Molecular cloning and characterization of a novel SGNH arylesterase from the goat rumen contents, Applied Microbiology and Biotechnology 91(6) (2011) 1561-1570.

    [14] G. Wang, H. Luo, Y. Wang, H. Huang, P. Shi, P. Yang, K. Meng, Y. Bai, B. Yao*, A novel cold-active xylanase gene from the environmental DNA of goat rumen contents direct cloning, expression and enzyme characterization, Bioresource Technology 102(3) (2011) 3330-3336.

    [15] G. Wang, H. Luo, K. Meng, Y. Wang, H. Huang, P. Shi, X. Pan, P. Yang, Q. Diao, H. Zhang, B. Yao*, High genetic diversity and different distributions of glycosyl hydrolase family 10 and 11 xylanases in the goat rumen, PloS One 6(2) (2011) e16731.

    [16] G. Wang, Y. Wang, P. Yang, H. Luo, H. Huang, P. Shi, K. Meng, B. Yao*, Molecular detection and diversity of xylanase genes in alpine tundra soil, Applied Microbiology and Biotechnology 87(4) (2010) 1383-1393.

    [17] H. Huang#, G. Wang#, Y. Zhao, P. Shi, H. Luo, B. Yao*, Direct and efficient cloning of full-length genes from environmental DNA by RT-qPCR and modified TAIL-PCR, Applied Microbiology and Biotechnology 87(3) (2010) 1141-1149.

    获奖情况

    中国农业科学院优秀博士论文(2012)

    福建省高校杰出青年人才(2015)

    指导研究生获得福建省优秀硕士论文(2017)